Understanding COVID-19 Antibodies Testing after Vaccination
Using a small blood sample, this post-vaccination antibody test is useful for determining if your immune system has developed certain type of antibodies after vaccination against SARS-CoV-2 virus.
An immune response can be detected a few days/weeks after individuals have received a vaccine against COVID-19.
Presently, the 2020/21 COVID-19 vaccines appear to offer some immunity against the common 2020 and some newer SARS-CoV-2 variant strains first discovered in the UK (B.1.1.7) and South Africa (B.1.351).
Studies of vaccine efficacy are showing antibodies being present soon after the first vaccine dose and the second shot serves as a booster for the body to continue to mount an antibodies response.
Today, we cannot draw the conclusion that long-term immunity against COVID-19 exists after one round of vaccinations. As variant strains evolve, it is likely we will need additional vaccinations against new strains to minimize the risk getting sick again.
The presence, and later absence of antibodies, may not mean that all immunity has been lost as there is evidence that our body’s immune system has ‘memory’ of antibodies against strains we’ve been infected with or exposed to via vaccination.
Coronaviruses (CoV) are a large family of viruses that cause illness ranging from common cold to more severe diseases such as Middle East Respiratory Syndrome (MERS-CoV) and Severe Acute Respiratory Syndrome (SARS-CoV). The novel coronavirus now known as the SARS-CoV-2 is a new strain which has not previously been identified in humans.
The core protein of SARS-CoV-2 is the N protein (Nucleocapsid protein), which is a protein component located inside the virus and is often used as a tool for diagnosis of coronaviruses.
From a naturally acquired COVID-19 infection from the community, our immune system develops antibodies against both the spike protein (S-protein) and nucleocapsid protein (N-protein) portions of the virus.
In Wave 1 and Wave 2 of the pandemic, most laboratory and rapid cartridge antibodies testing platforms were focused on DETECTING recent natural infection by identifying antibodies against the less mutagenic N-protein.
In contrast, man-made vaccines contain only some components of the S-protein to stimulate antibodies response.
Therefore, to detect antibodies triggered by vaccination, it will require that we identify antibodies against the COVID-19 S-protein. Only the newer laboratory based platforms can provide this specificity. No Rapid Cartridge Antibodies test kits presently in the marketplace can confirm it does test for such S-protein antibodies.
Graphic representation of how antibodies bind to antigen targets and how the lab can ‘read it’ in video below.
Two Testing Options to Detect Antibodies Post Vaccination
Coming soon, we are engaging with a Canadian Laboratory in British Columbia to offer you detection of antibodies against COVID-19 because of vaccinations.
More importantly, we will be offering the ability to identify what strains of COVID-19 your antibodies are effective against, including ongoing newer variant strains.
1) Testing at a point in time
2) Subscription model over 1 year of repeat testing
Blood Spot Collection Options
Self-Test Blood Spot Collection
Your kit will contain all the necessary supplies for self-collection in the comfort of your own home. The test only requires you to fill 3 circles with 2 drops of blood in each circle. You will collect your blood sample using the paper blot included in your kit.
Clinic Lab Blood Draw
Attend Executive Health Centre for a blood draw